Induction of angiogenic chemokine CCL2 by human herpesvirus 8 chemokine receptor
نویسندگان
چکیده
منابع مشابه
The human herpesvirus 8 chemokine receptor vGPCR triggers autonomous proliferation of endothelial cells.
We have used a novel conditional transgenic system to study the mechanisms of angioproliferation induced by viral G protein-coupled receptor (vGPCR), the constitutively active chemokine receptor encoded by human herpesvirus 8 (HHV8, also known as Kaposi sarcoma herpesvirus). Using this system, we were able to control temporal expression of vGPCR and to monitor its expression in situ via the use...
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ژورنال
عنوان ژورنال: Virology
سال: 2010
ISSN: 0042-6822
DOI: 10.1016/j.virol.2009.11.024